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本產(chǎn)品僅用于科研，不用于臨床

英文名稱 Anti-NMS/Neuromedin S
中文名稱 神經(jīng)調(diào)節(jié)肽S抗體
別 名 Neuromedin S; Neuromedin-S; Nms; NMS_HUMAN; Prepro NMS.
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Dog
產(chǎn)品類型 一抗
研究領(lǐng)域 腫瘤 心血管 神經(jīng)生物學 信號轉(zhuǎn)導 生長因子和激素 新陳代謝
蛋白分子量 predicted molecular weight: 4kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Neuromedin S
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 NMS is a 153 amino acid secreted protein that belongs to the NmU family. NMS is implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. The gene that encodes NMS consists of approximay 12,799 bases and maps to human chromosome 2q11.2. Consisting of 237 million bases and encoding over 1,400 genes, chromosome 2 makes up approximay 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8.
Function : NMS （neuromedin S） is a 36-amino acid neuropeptide specifically expressed in the suprachiasmatic nucleus （SCN） of the hypothalamus. NMS shares a C-terminal core structure with NMU. NMS mRNA is highly expressed in the central nervous system, spleen and testis. NMS may be implicated in the regulation of circadian rhythms and feeding behavior.
Subcellular Location : Secreted
Similarity : Belongs to the NmU family.
Database links : UniProtKB/Swiss-Prot: Q5H8A3.1

宿主：Human、Murine、Rat （Rattus）、Bovine、Dog （Canine）等物種
神經(jīng)調(diào)節(jié)肽S抗體應用范圍: WB, ELISA, IP, IHC （p）, IHC （f）, IF
緩沖液：0.01m PBS,pH值7.4和10毫克/毫升BSA
儲存液：0.1%（w/v）*          

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